Great things from great collaborations! Together with the Lab of Hartmut Hengel at the Dept of Virology we discovered a new way in which B cells can hijack the adaptive immune system. We show that CMV viral glycoprotein can specifically target IgG+ memory B cells. This study is now out in EMBO Molecular Medicine.
Precious Cramer and Stefan Neys great job!! And thanks to all contributors for this collaborative work!
The paper:
A viral glycoprotein targets IgG+ memory B cells to mediate humoral immune evasion.
Cramer P, Neys SFH, Fiedler M, Lorenzetti R, Reinhard H, Janowska I, Staniek J, Kohl AK, Hadlova P, Huber M, Plachter B, Read C, Falcone V, von Einem J, Hoffmann K, Lenac Rovis T, Jonjic S, Kolb P, Rizzi M, Hengel H.
EMBO Mol Med. 2026 Jan 20. doi: 10.1038/s44321-026-00372-1. Online ahead of print. PMID: 41559372