Laboratory of Prof. Marta Rizzi, Freiburg and Vienna

Taking a closer look at human B lymphopoiesis – Franziska Schmidt digs deep in defects of B cell reconstitution and modeling methods

We are very happy to share a new review led by our PhD student Franziska Schmidt on human B lymphopoiesis.

The review discusses key challenges in B cell reconstitution in clinical settings such as HSCT, and highlights recent advances in in vitro modeling approaches to better study human B cell development.

Together, these systems are helping to close important gaps in our understanding of how human B cells develop and how reconstitution can be improved.

Great work, Franzi!

The review:

Human B-lymphopoiesis: Clinical challenges in B cell reconstitution and advances in in vitro modeling.

Schmidt FM, Rizzi M.

Immunol Lett. 2026 Feb;277:107106. doi: 10.1016/j.imlet.2025.107106. Epub 2025 Nov 3. PMID: 41192681 

← Back